| Alan Alda | Senator Arnold Vinick |
| Kristin Chenoweth | Annabeth Schott |
| Allison Janney | C.J. Cregg |
| Joshua Malina | Will Bailey |
| Mary McCormack | Kate Harper |
| Janel Moloney | Donna Moss |
| Richard Schiff | Toby Ziegler |
| John Spencer | Leo McGarry |
| Bradley Whitford | Josh Lyman |
| Jimmy Smits | Matthew Santos |
| Martin Sheen | President Josiah Bartlet |
| Janeane Garofalo | Louise Thornton |
| Jon Bon Jovi | Jon Bon Jovi |
| Teri Polo | Helen Santos |
| Kathleen York | Andrea Wyatt |
| John Aylward | Barry Goodwin - Former DNC Chair |
| Lee Garlington | Alana Waterman |
| Matt Letscher | Mr. Blake - U.S. Attorney |
| Ramon De Ocampo | Otto |
| David Ramsey | Teddy - Santos' Turnout Briefer |
| Joshua Cabrera | Peter Santos |
| Ashlyn Sanchez | Miranda Santos |
| Francesca Ferrara | Local Reporter #1 |
| Daphna Cardinale | Reporter #2 |
| Eric Christie | Reporter #3 |
| Ivan Allen | News Anchor Roger Salier |
| Loren Lester | Jarin |
| Dylan Naber | Huck Ziegler |
| Alexis Cardenas | Molly |
| Kylie Cardenas | Molly |
| Glenda Morgan Brown | Woman |
| Robert Aguilar Jr. | Marine Guard |
| Timothy Davis-Reed | Mark O'Donnell |
| Sean R. Lake | Millworker |
| Brettney Perr | Neighbor |