| Stockard Channing | Abbey Bartlet |
| Dulé Hill | Charlie Young |
| Allison Janney | C.J. Cregg |
| Joshua Malina | Will Bailey
(credit only) |
| Mary McCormack | Kate Harper |
| Janel Moloney | Donna Moss
(credit only) |
| Richard Schiff | Toby Ziegler |
| John Spencer | Leo McGarry |
| Bradley Whitford | Josh Lyman
(credit only) |
| Jimmy Smits | Matthew Santos
(credit only) |
| Martin Sheen | President Josiah Bartlet |
| Kristin Chenoweth | Annabeth Schott |
| Christopher Lloyd | Professor Lawrence Lessig |
| Roger Rees | Brit. Ambassador Lord John Marbury |
| Steve Ryan | Secretary of Defense Miles Hutchinson |
| Elya Baskin | Mr. Zubatov |
| Anthony Azizi | Asefi Hossein Kamal 'Chet' Bin Hamid |
| NiCole Robinson | Margaret Hooper |
| Renée Estevez | Nancy |
| Melissa Fitzgerald | Carol |
| Peter James Smith | Ed |
| William Duffy | Larry |
| Ben Murray | Curtis |
| Charles Noland | Steve |
| Ron Ostrow | John |
| Tom Chick | Gordon
(as Tom W. Chick) |
| Penny Griego | Newscaster |
| Derek Coleman | Secret Service |
| Pamela Salem | P.M. Maureen Graty |
| Oleg Vidov | Lipecki |
| Edward Shkolnikov | Helakal |
| Claudia Lynx | Miss World |
| Ken Weiler | Officer |
| Robert Aguilar Jr. | Marine Guard
(uncredited) |
| Alan Alda | Senator Arnold Vinick
(uncredited) |