| Rob Lowe | Sam Seaborn |
| Stockard Channing | Abbey Bartlet |
| Dulé Hill | Charlie Young |
| Allison Janney | C.J. Cregg |
| Janel Moloney | Donna Moss |
| Richard Schiff | Toby Ziegler |
| John Spencer | Leo McGarry |
| Bradley Whitford | Josh Lyman |
| Martin Sheen | President Josiah Bartlet |
| Mary-Louise Parker | Amy Gardner |
| Ron Silver | Bruno Gianelli |
| Joshua Malina | Will Bailey |
| Christian Slater | Lt. Cmdr. Jack Reese |
| Kathleen York | Andrea Wyatt |
| Joanna Gleason | Atty. Jordon Kendall |
| Tobin Bell | Colonel Whitcomb |
| Danica McKellar | Elsie Snuffin |
| Gina Hecht | Julie, Panel Moderator on TV |
| Victor Raider-Wexler | Bernie, Panel Member on TV |
| Thomas Kopache | Assistant Secretary of State Bob Slatterly |
| Wendy Braun | Gail Mackee |
| Nick Jameson | Martin Avery |
| Tim Silva | George, Panel Member on TV |
| Devika Parikh | Bonnie |
| Kim Webster | Ginger |
| William Duffy | Larry |
| Melissa Fitzgerald | Carol Fitzpatrick |
| Peter James Smith | Ed |
| Marc Lynn | Chris Whitaker |
| Christopher May | Tom, Wyatt Staffer |
| Diane Hsu | Campaign Aide |
| Rae Ritke | Ashley |
| Symba | Annette |
| Dawn A. Douglas | FBI Agent |