| Rob Lowe | Sam Seaborn |
| Stockard Channing | Abbey Bartlet |
| Dulé Hill | Charlie Young |
| Allison Janney | C.J. Cregg |
| Janel Moloney | Donna Moss |
| Richard Schiff | Toby Ziegler |
| John Spencer | Leo McGarry |
| Bradley Whitford | Josh Lyman |
| Martin Sheen | President Josiah Bartlet |
| Ron Silver | Bruno Gianelli |
| Gary Farmer | Jack Lone Feather |
| Renée Estevez | Nancy |
| NiCole Robinson | Margaret Hooper |
| Georgina Lightning | Maggie Morningstar Charles |
| Armando Pucci | Alberto Fedrigotti, Italian Chargé d'Affaires |
| Jenny Gago | Bernice Collette, OMB |
| Shashawnee Hall | Russell Angler |
| Dave Hager | DeKalb Cty. D.A. Mark Farragut |
| Kim Webster | Ginger |
| Melissa Fitzgerald | Carol Fitzpatrick |
| Timothy Davis-Reed | Mark O'Donnell |
| Patrick O'Connell | Bartender |
| Ana Gasteyer | Butterball Hotline Operator
(uncredited) |
| Sean Allen Jones | Uniformed Secret Service Agent
(uncredited) |