| Kevin Bacon | Ryan Hardy |
| Jeananne Goossen | Jennifer Mason |
| Natalie Zea | Claire Matthews |
| Shawn Ashmore | Mike Weston |
| Valorie Curry | Emma Hill |
| Nico Tortorella | Jacob Wells |
| Adan Canto | Paul Torres |
| Kyle Catlett | Joey Matthews |
| Maggie Grace | Sarah Fuller |
| James Purefoy | Joe Carroll |
| Billy Brown | Troy Riley |
| John Lafayette | Marshall Turner |
| Steve Monroe | Jordy Raines |
| Michael Roark | Detective Warren |
| Melissa Ponzio | Detective Joan Garcia |
| Stephanie Leigh Schlund | Annie |
| Cheri Christian | Ice Pick Lady |
| Michelle Li | Female Reporter |
| Jason Benjamin | Guard #1 |
| Hunter Womack | Guard #2 |
| Edloe Blackwell | Harriet |
| Carissa Fowler | Linda |
| Susan Walters | Prosecutor |
| Terrence Gibney | Psychologist |
| Jessica Luza | Sexy Brunette |
| Des Epps | Student #1 |
| Amanda Davis | News Anchor Affiliate #1 |
| Tom Haynes | News Anchor Affiliate #2 |
| Lisa Tucker | News Anchor Affiliate #3 |
| John Emil D'Angelo | Detective |
| Alexander Martin Jones | US Marshall |
| Bobby Nash | FBI Agent Edwards |
| Loren L. Baker | FBI Forensic Photographer |
| James Busler | Coroner |
| Matt Clanton | FBI Agent |
| Ludovic Coutaud | Upscale Resident |
| Andrew Fincher | Uniform Officer |
| Andrew Gostel | News Reporter |
| Jon Gould | FBI Agent |
| Joshua Grant | Cameraman |
| Jaime Griffon | Reporter |
| Bradford Haynes | Virginia Homicide Detective |
| Walter Hendrix III | Waverly Detective |
| Andrew S. McMillan | Officer Kirkland |
| Wayne Packer | Police Officer |
| Marcus Deshaun Richardson | Guard #7 |
| Jason Roach | FBI Agent |
| Megan Monaghan Smith | CSI Technician |
| Kelly Spicer | Female Jogger |
| Errol Suleyman | Officer |
| Don Teems | F.B.I. Agent |
| Jeff Trink | FBI Crime Scene Photographer |
| Shawn Watwood | Inmate |
| Thomas Yungerberg | Student |