| Liam McIntyre | Spartacus |
| Manu Bennett | Crixus |
| Dustin Clare | Gannicus |
| Daniel Feuerriegel | Agron
(as Dan Feuerriegel) |
| Cynthia Addai-Robinson | Naevia |
| Simon Merrells | Crassus |
| Ellen Hollman | Saxa |
| Pana Hema Taylor | Nasir
(as Pana Hema-Taylor) |
| Jenna Lind | Kore |
| Christian Antidormi | Tiberius Crassus |
| Anna Hutchison | Laeta |
| Todd Lasance | Caesar |
| Barry Duffield | Lugo |
| Gwendoline Taylor | Sibyl |
| Blessing Mokgohloa | Castus |
| Roy Snow | Commander Rufus |
| Tineke Robson | Opelia
(as T. Ann Robson) |
| Will Hall | Dour Soldier |
| Joel Herbert | Pleuratos |
| Joshua Randall | Mettius
(as Josh Randall) |
| Bryce Langston | Messenger |
| Tyrone Bell | Rebel
(uncredited) |
| Shane Blakey | The Veteran
(uncredited) |
| Rosalie Button | Rebel
(uncredited) |
| Vanessa Cater | Verenda
(archive footage) (uncredited) |
| Tim Eccles | Timocles
(uncredited) |
| Ashlee Fidow | Rebel
(uncredited) |
| Paul Hallett | High Ranking Roman Soldier
(uncredited) |
| Jason Lambert | Brictius
(archive footage) (uncredited) |
| Lauren Shaw | Rebel
(uncredited) |
| Andrew Stehlin | Rabanus
(uncredited) |
| Kelvin Taylor | Kraynos
(uncredited) |
| Graham Vincent | Pollux
(uncredited) |