| Charlie Hunnam | Jackson 'Jax' Teller |
| Katey Sagal | Gemma Teller Morrow |
| Mark Boone Junior | Robert 'Bobby Elvis' Munson |
| Dayton Callie | Wayne Unser |
| Kim Coates | Alexander 'Tig' Trager |
| Tommy Flanagan | Filip 'Chibs' Telford |
| Ryan Hurst | Harry 'Opie' Winston |
| Theo Rossi | Juan Carlos 'Juice' Ortiz |
| Maggie Siff | Dr. Tara Knowles |
| Ron Perlman | Clarence 'Clay' Morrow |
| Danny Trejo | Romero 'Romeo' Parada |
| Benito Martinez | Luis Torres |
| Rockmond Dunbar | Lieutenant Eli Roosevelt |
| Harold Perrineau | Damon Pope |
| Jimmy Smits | Nero Padilla |
| Michael Ornstein | Chuck 'Chucky' Marstein |
| David Labrava | Happy Lowman |
| Rachel Miner | Dawn 'Margaux' Trager |
| Billy Brown | August Marks |
| Wanda De Jesus | Carla |
| Chuck Zito | Frankie Diamonds |
| Chris Browning | Gogo |
| Kurt Yaeger | Greg the Peg |
| Niko Nicotera | George 'Ratboy' Skogstrom |
| Chris Reed | Philip 'Filthy Phil' Russell |
| B.J. Britt | Darnell |
| Mo McRae | Tyler |
| LaMonica Garrett | Deputy Sheriff Cane |
| Derek Anthony | Detective Goodman |
| Bryan Rasmussen | Cleaner |
| ReShaun Groomes | Pope's Muscle |
| Runa Lucienne | Escort |
| Sophia Markov | Thomas |
| Victoria Markov | Thomas |
| Jocelyn Osorio | Hot Latina |
| Vanessa Sheri | Crow Eater |
| Natalie Skyy | Olsen Twin |
| Bobby Waldron | Boz |
| Steve Wilcox | Masked Man |