| Charlie Hunnam | Jackson 'Jax' Teller |
| Katey Sagal | Gemma Teller Morrow |
| Mark Boone Junior | Robert 'Bobby Elvis' Munson |
| Kim Coates | Alexander 'Tig' Trager |
| Tommy Flanagan | Filip 'Chibs' Telford |
| Ryan Hurst | Harry 'Opie' Winston |
| Johnny Lewis | Kip 'Half Sack' Epps |
| William Lucking | Piermont 'Piney' Winston |
| Theo Rossi | Juan Carlos 'Juice' Ortiz
(credit only) |
| Maggie Siff | Dr. Tara Knowles |
| Ron Perlman | Clarence 'Clay' Morrow |
| Adam Arkin | Ethan Zobelle |
| Dayton Callie | Chief Wayne Unser |
| Jamie McShane | Cameron Hayes |
| Callard Harris | Edmond Hayes |
| Henry Rollins | AJ Weston |
| McNally Sagal | Margaret Murphy |
| David Labrava | Happy |
| Cassandra Braden | Admitting Nurse |
| David Aranovich | ER Doctor |
| Joe Rose | SOA Oregon Leader |
| Josh Latzer | Bounty Hunter |
| Caroline Choi | Young Clerical |
| Terri Crawford | Angry Woman
(uncredited) |
| Holly Harris | Bar Patron
(uncredited) |
| Kanin Howell | Bounty Hunter #4
(uncredited) |
| Dennis Keiffer | Izzy
(uncredited) |
| Ryan Van de Kamp Buchanan | EMT Paramedic
(uncredited) |