| Thomas Middleditch | Richard Hendricks |
| T.J. Miller | Erlich Bachman |
| Josh Brener | Nelson 'Big Head' Bighetti |
| Martin Starr | Bertram Gilfoyle |
| Kumail Nanjiani | Dinesh Chugtai |
| Amanda Crew | Monica Hall |
| Zach Woods | Donald 'Jared' Dunn |
| Matt Ross | Gavin Belson
(credit only) |
| Suzanne Cryer | Laurie Bream |
| Jimmy O. Yang | Jian Yang
(credit only) |
| Annie Sertich | C.J. Cantwell |
| Frank Birney | Old Man |
| Erin Breen | Jan |
| Keye Chen | Dang |
| Dustyn Gulledge | Evan |
| Chelsey Ireland | Receptionist |
| Phillip Jeanmarie | Don |
| Eddie Liu | Doug |
| J. Mandyam | Sanjay
(as Jay Mandyam) |
| Shannon McClung | Keith |
| Miljan Milosevic | Gleb |
| Sigrid Owen | Elisabet |
| Azie Tesfai | Dawn Simon |
| Rosemary Napoli | Yard sale shopper
(uncredited) |