| Thomas Middleditch | Richard Hendricks |
| T.J. Miller | Erlich Bachman |
| Josh Brener | Nelson 'Big Head' Bighetti |
| Martin Starr | Bertram Gilfoyle |
| Kumail Nanjiani | Dinesh Chugtai |
| Amanda Crew | Monica Hall |
| Zach Woods | Donald 'Jared' Dunn |
| Matt Ross | Gavin Belson |
| Suzanne Cryer | Laurie Bream |
| Jimmy O. Yang | Jian Yang
(credit only) |
| Jill E. Alexander | Patrice
(as Jill Alexander) |
| Aly Mawji | Naveen Dutt |
| Scott Prendergast | Scott |
| Rogelio T. Ramos | Another Executive
(as Rogelio Ramos) |
| Brian Tichnell | Jason |
| Ben Feldman | Ron LaFlamme |
| Matt McCoy | Pete Monahan |
| Gabriel Tigerman | Gary Irving |
| Stephen Tobolowsky | Jack Barker |
| Bernard White | Spiritual Advisor |
| Emily Chang | Emily Chang |
| Willis Chung | |
| Cate Cohen | Melinda |
| Dustyn Gulledge | Evan |
| Arthur Keng | Alan |
| Mariano 'Big Dawg' Mendoza | Prison Guard
(as Mariano Mendoza) |
| Casey O'Farrell | Pete |
| Diallo Riddle | Paul |
| Skyler Seymour | Flutterbeam Founder #1 |
| Alex Skinner | Flutterbeam Founder #2 |
| David Storch | Hooli Lawyer |
| Brad Stone | Brad Stone |
| Mike Ferguson | Prisoner
(uncredited) |
| Samir Patel | Hooli Employee /
Flutterbeam Employee
(uncredited) |
| Samuel Platt | Hooli Employee
(uncredited) |