| Thomas Middleditch | Richard Hendricks |
| T.J. Miller | Erlich Bachman |
| Josh Brener | Nelson 'Big Head' Bighetti |
| Martin Starr | Bertram Gilfoyle |
| Kumail Nanjiani | Dinesh Chugtai |
| Amanda Crew | Monica Hall |
| Zach Woods | Donald 'Jared' Dunn |
| Matt Ross | Gavin Belson |
| Suzanne Cryer | Laurie Bream |
| Jimmy O. Yang | Jian Yang
(credit only) |
| Frank Collison | Noah |
| Patrick Daniel | Tech Guy |
| Chris Diamantopoulos | Russ Hanneman |
| Matt McCoy | Pete Monahan |
| Alyson Reed | Louise |
| Karen Strassman | Hooli Lead Counsel |
| Bernard White | Spiritual Advisor |
| Joseph Auger | Bus Driver
(as Joe Auger) |
| Diane Chernansky | Heidi Evans |
| Taylor Coffman | Marketing Executive |
| Dustyn Gulledge | Evan |
| Jules Hartley | Hooli Assistant Counsel |
| Anna Khaja | Rachel |
| Bart McCarthy | Judge Underwood |
| Stephanie Rose Feldman | |
| Brigitte Valdez | Barista |
| Ping Wu | Henry |
| Cassidy Barnes | Tech Hipster
(uncredited) |
| Noelle Bonhomme | Jogger
(uncredited) |