| Liev Schreiber | Ray Donovan |
| Eddie Marsan | Terry Donovan |
| Dash Mihok | Bunchy Donovan |
| Katherine Moennig | Lena |
| Pooch Hall | Daryll |
| Kerris Dorsey | Bridget Donovan |
| Devon Bagby | Conor Donovan |
| Graham Rogers | Smitty |
| Susan Sarandon | Samantha Winslow |
| Jon Voight | Mickey Donovan |
| Domenick Lombardozzi | Sean 'Mac' McGrath |
| Lola Glaudini | Anita Novak |
| Alyssa Diaz | Teresa |
| Tony Curran | Sgt. Mikey 'Rad' Radulovic |
| Zach Grenier | Ed Feratti |
| Max Casella | Emerson Lake |
| Chris Tardio | Danny Bianchi |
| Jacob Ming-Trent | Big Easy |
| Michael J. Burg | Ron Klitstein |
| Olivia Jennah Kadri | Maria |
| Sasha Kali Kadri | Maria |
| Michael Imperiale | Ringleader |
| Jillian Lindig | New York Dame |
| Tom Flynn | Wealthy Man |
| Danny Doherty | Military Guy |
| Rick Crom | Actual Priest |
| Pat Bowie | Old African-American Lady |
| Chris Barnes | Jitney Bus Driver |
| Kymbali Craig | Officer Pam |
| Marlene Hodgdon | Check Cashing Woman #1 |
| Pamela Afesi | Check Cashing Woman #2 |
| Chris McGinn | Check Cashing Woman #3 |
| Jamar Greene | Check Cashing Guard |
| Lauren S. Gordon | Dog Woman |
| Tim Lajcik | Polish Tony |
| Suki Úna Rae | Pedestrian |
| Christina Uniqe Castellanos | Psych Patient |
| David Cheekz Weeks | Bobby |
| Sam Zang | Pedestrian in Front of Gym |