| Patrick Stewart | Capt. Jean-Luc Picard |
| Jonathan Frakes | Cmdr. William Riker |
| LeVar Burton | Lt. Geordi La Forge |
| Denise Crosby | Lt. Tasha Yar
(credit only) |
| Michael Dorn | Lt. Worf |
| Gates McFadden | Dr. Beverly Crusher |
| Marina Sirtis | Counselor Deanna Troi |
| Brent Spiner | Lt. Cmdr. Data |
| Wil Wheaton | Wesley Crusher
(credit only) |
| Michelle Phillips | Jenice Manheim |
| Rod Loomis | Dr. Paul Manheim |
| Isabel García Lorca | Gabrielle
(as Isabel Lorca) |
| Dan Kern | Lt. Dean |
| Jean-Paul Vignon | Edouard |
| Kelly Ashmore | Francine |
| Lance Spellerberg | Transporter Chief Herbert |
| Majel Barrett | Enterprise Computer
(voice) (uncredited) |
| James G. Becker | Youngblood
(uncredited) |
| Dexter Clay | Operations Division Officer
(uncredited) |
| Susan Duchow | Operations Division Officer
(uncredited) |
| Nora Leonhardt | Science Division Ensign
(uncredited) |
| Tim McCormack | Ensign Bennett
(uncredited) |
| Lorine Mendell | Crewman Diana Giddings
(uncredited) |
| Guy Vardaman | Darien Wallace
(uncredited) |