| Evan Peters | Stan Bowes |
| Kate Mara | Patty Bowes |
| James Van Der Beek | Matt Bromley |
| Michaela Jaé (MJ) Rodriguez | Blanca Rodriguez
(as MJ Rodriguez) |
| Dominique Jackson | Elektra |
| Billy Porter | Pray Tell |
| Indya Moore | Angel |
| Ryan Jamaal Swain | Damon Richards |
| Charlayne Woodard | Helena St. Rogers |
| Dyllon Burnside | Ricky
(as Dyllón Burnside) |
| Hailie Sahar | Lulu |
| Angelica Ross | Candy |
| Angel Bismark Curiel | Lil Papi |
| Kathryn Erbe | Dr. Gottfried |
| Christine Ebersole | Bobbi |
| Samantha Grace Blumm | Amanda Bowes |
| Glamo | Tony |
| Ian Lowe | Salesman |
| Alysia Joy Powell | Westside Nurse |
| Bonnie Rose | Secretary |
| Johnny Sibilly | Costas |
| Galen J. Williams | Marcus |
| Sandy York | Nurse |
| Chandler Akpovwa | Ballroom Attendee
(uncredited) |
| Brian Donahue | Santa
(uncredited) |
| Andrew Henkelman | Business Executive
(uncredited) |
| Emery Johnson | Stone Cold Face Walker
(uncredited) |
| Jason A. Rodriguez | Lemar
(uncredited) |
| B. Hawk Snipes | Runway Contestant
(uncredited) |
| Justin Triest | Business Executive
(uncredited) |