| Taylor Schilling | Piper Chapman |
| Natasha Lyonne | Nicky Nichols |
| Uzo Aduba | Suzanne 'Crazy Eyes' Warren |
| Danielle Brooks | Tasha 'Taystee' Jefferson |
| Jackie Cruz | Marisol 'Flaca' Gonzales |
| Laura Gómez | Blanca Flores |
| Selenis Leyva | Gloria Mendoza |
| Taryn Manning | Tiffany 'Pennsatucky' Doggett |
| Adrienne C. Moore | Cindy Hayes |
| Matt Peters | Joel Luschek |
| Jessica Pimentel | Maria Ruiz |
| Dascha Polanco | Dayanara Diaz |
| Alysia Reiner | Natalie Figueroa |
| Elizabeth Rodriguez | Aleida Diaz |
| Nick Sandow | Joe Caputo |
| Dale Soules | Frieda Berlin |
| Yael Stone | Lorna Morello |
| Kate Mulgrew | Galina 'Red' Reznikov |
| Laura Prepon | Alex Vause |
| Michael Chernus | Cal Chapman |
| Tracee Chimo Pallero | Neri Feldman |
| Daniella De Jesús | Zirconia Cabrera |
| Shannon Esper | Alana Dwight |
| Joel Marsh Garland | Scott O'Neill |
| Susan Heyward | Tamika Ward |
| Mike Houston | CO Lee Dixon |
| Rebecca Knox | Tina Swope |
| Lauren Lapkus | Susan Fischer |
| Sipiwe Moyo | Adeola |
| Shirley Roeca | Juanita Vazquez |
| Adam Rothenberg | Mr. Doggett |
| Emily Tarver | CO Artesian McCullough |
| Greg Vrotsos | CO Hellman |
| Nicholas Webber | CO Alvarez |
| Lori Petty | Lolly Whitehill |
| Michael Harney | Sam Healy |
| Besanya Santiago | Creech |
| Phumzile Sitole | Akers |
| Marie-Lou Nahhas | Shani Abboud |
| Mandela Bellamy | Rosalie Deitland |
| Karina Arroyave | Karla Córdova |
| Adam Lindo | Carlos 'Clitvack' Litvack |
| Tuli Roy-Kirwan | Swapna Majumdar |
| Mike Cabellon | Elmer Fantauzzo |
| Brianna Gonzalez-Bonacci | Christina Diaz |
| Isabella Ferreira | Eva Diaz |
| Nicholas Daniel Gonzalez | Emiliano Diaz |
| Monica Rae Summers Gonzalez | Gabriella |
| Melinna Bobadilla | Santos Chaj |
| Stephen Christopher Marshall | Big Gene |
| Will Meyers | Little Gene |
| Yurie Collins | Corinna |
| Esteban Benito | Jordan |
| Jenson Smith | Rivka |
| Mindee Aviva | Inmate |
| Carla Carvalho | Ice Detainee |
| Tiffany Jaide Hightower | Inmate |
| Claudette Lalí | Inmate |
| Alex Perez | CO Officer |