| Taylor Schilling | Piper Chapman |
| Uzo Aduba | Suzanne 'Crazy Eyes' Warren |
| Danielle Brooks | Tasha 'Taystee' Jefferson |
| Michael Harney | Sam Healy |
| Natasha Lyonne | Nicky Nichols |
| Taryn Manning | Tiffany 'Pennsatucky' Doggett |
| Kate Mulgrew | Galina 'Red' Reznikov |
| Jason Biggs | Larry Bloom |
| Michael Chernus | Cal Chapman |
| Tracee Chimo Pallero | Neri Feldman |
| Catherine Curtin | Wanda Bell |
| Lea DeLaria | Big Boo |
| Yvette Freeman | Irma |
| Joel Marsh Garland | Scott O'Neill |
| Annie Golden | Norma Romano |
| Selenis Leyva | Gloria Mendoza |
| Deirdre Lovejoy | Chris Maser |
| Matt McGorry | John Bennett |
| Dascha Polanco | Dayanara Diaz |
| Judith Roberts | Taslitz |
| Deborah Rush | Carol Chapman |
| Nick Sandow | Joe Caputo |
| Constance Shulman | Yoga Jones |
| Dale Soules | Frieda Berlin |
| Yael Stone | Lorna Morello |
| Lorraine Toussaint | Yvonne 'Vee' Parker |
| Lin Tucci | Anita DeMarco |
| Samira Wiley | Poussey Washington |
| Pablo Schreiber | George 'Pornstache' Mendez |
| Jackie Cruz | Marisol 'Flaca' Gonzales |
| Beth Fowler | Sister Jane Ingalls |
| Kimiko Glenn | Brook Soso |
| Diane Guerrero | Maritza Ramos |
| Vicky Jeudy | Janae Watson |
| Mary Looram | Celeste Chapman |
| Emma Myles | Leanne Taylor |
| Jessica Pimentel | Maria Ruiz |
| Barbara Rosenblat | Miss Rosa Cisneros |
| Abigail Savage | Gina Murphy |
| Sidné Anderson | Rhonda |
| Brendan Burke | Wade Donaldson |
| Bill Hoag | Bill Chapman |
| Leslie Lyles | Louise |
| Michael Richey | Gene |
| Victor Truro | Priest |
| Nikki E. Walker | Chivas |
| Regina Hardy | Inmate Vee's Gang Member |
| Shaleeni Ranchhod | Inmate |
| Eric J Carlson | Corrections Officer |
| Lauren Garlick | Inmate |
| Christine Glover | Inmate |
| Kerry Logan | Chapman Family |
| Ashley North | Prisoner in AA Meeting |
| Thelma O'Leary | Prison Inmate |
| Angela Palmer-Haibach | Inmate |
| Jason Parks | Chapman Family |
| Shiela Rodriguez | Prison Inmate |
| Richard Stanislaw | Chapman Family |