| Mark Harmon | Leroy Jethro Gibbs |
| Michael Weatherly | Anthony DiNozzo |
| Cote de Pablo | Ziva David |
| Pauley Perrette | Abby Sciuto |
| Sean Murray | Timothy McGee |
| Rocky Carroll | Leon Vance |
| David McCallum | Donald Mallard |
| Arnold Vosloo | Mossad Officer Amit Hadar |
| Michael O'Neill | Former NCIS Special Agent Riley McCallister |
| Catherine Dent | Whitney Sharp |
| T.J. Ramini | Mossad Officer Malachi Ben-Gidon |
| Sarai Givaty | Mossad Officer Liat Tuvia |
| Oren Dayan | Karif Yasin |
| Stan Ivar | Former NCIS Special Agent Ben Robinson |
| Leslie-Anne Panaligan | Hillary Lange |
| Michael Nouri | Mossad Director Eli David |
| Alex Morris | Former NCIS Special Agent Kurt Nelson |
| Maura Soden | Former NCIS Special Agent Melora Koss |
| Zoli Dora | Ramzi Ashor |
| Abraham Justice | Abasi Al-Masri |
| Justin Reed | Washington D.C. Patron |