| Jon Hamm | Don Draper |
| Elisabeth Moss | Peggy Olson |
| Vincent Kartheiser | Pete Campbell
(credit only) |
| January Jones | Betty Francis |
| Christina Hendricks | Joan Harris |
| Aaron Staton | Ken Cosgrove |
| Rich Sommer | Harry Crane |
| Kiernan Shipka | Sally Draper
(credit only) |
| Jessica Paré | Megan Draper |
| Kevin Rahm | Ted Chaough
(credit only) |
| Christopher Stanley | Henry Francis |
| Jay R. Ferguson | Stan Rizzo |
| Ben Feldman | Michael Ginsberg |
| Mason Vale Cotton | Bobby Draper |
| Robert Morse | Bertram Cooper |
| John Slattery | Roger Sterling |
| Harry Hamlin | Jim Cutler |
| Teyonah Parris | Dawn Chambers |
| Allan Havey | Lou Avery |
| Anne Dudek | Francine Hanson |
| Trevor Einhorn | John Mathis |
| Sola Bamis | Shirley |
| David James Elliott | Dave Wooster |
| Johnathan McClain | Alan Silver |
| Pat Skipper | Tom Pruitt |
| Kandis Fay | Pam Keyser
(as Kandis Erickson) |
| Beth Hall | Caroline |
| Evan Londo | Gene Draper |
| Ryder Londo | Gene Draper |
| Kit Williamson | Ed |
| Stephanie Drake | Meredith |
| Rachel DiPillo | Sherry |
| Kirstin Ford | Tricia |
| Pamela Shaddock | Loretta |
| Jim Metzler | Victor Perkins |
| Brandi Burkhardt | Emily Arnett |
| Aynsley Bubbico | Rose Marie |
| Worth Howe | Cyrus |
| Alice Borcean | SCP Lady
(uncredited) |
| Craig Calman | SC&P Male
(uncredited) |
| Wayo Dorsey | SC&P Office Male
(uncredited) |
| Haley Lyn Gilchrist | Susie Rogers
(uncredited) |
| Cheyenne Nugent | SC&P Secretary
(uncredited) |
| Hudson Phillips | SC&P Employee
(uncredited) |