| Jon Hamm | Don Draper |
| Elisabeth Moss | Peggy Olson |
| Vincent Kartheiser | Pete Campbell |
| January Jones | Betty Francis
(credit only) |
| Christina Hendricks | Joan Harris |
| Aaron Staton | Ken Cosgrove |
| Rich Sommer | Harry Crane
(credit only) |
| Kiernan Shipka | Sally Draper
(credit only) |
| Jessica Paré | Megan Draper |
| Kevin Rahm | Ted Chaough |
| Christopher Stanley | Henry Francis
(credit only) |
| Jay R. Ferguson | Stan Rizzo |
| Ben Feldman | Michael Ginsberg |
| Mason Vale Cotton | Bobby Draper
(credit only) |
| Robert Morse | Bertram Cooper |
| John Slattery | Roger Sterling |
| Alison Brie | Trudy Campbell |
| Julia Ormond | Marie Calvet |
| James Wolk | Bob Benson |
| Charlie Hofheimer | Abe Drexler |
| Brian Markinson | Dr. Arnold Rosen |
| Gary Basaraba | Herb Rennet |
| Harry Hamlin | Jim Cutler |
| Craig Anton | Frank Gleason |
| Joe O'Connor | Tom Vogel |
| Peter Mackenzie | Cliff Perry |
| Danielle Panabaker | Daisy McCluskey |
| Matthew Kimbrough | Mikey O'Brien |
| Sarah Aldrich | Peaches Rennet |
| Beth Hall | Caroline |
| Barrett Shuler | Scott Hagan |
| Tracy Silver | Margie Koch |
| Christine Garver | Moira |
| Courtney Taylor Burness | Pat |
| Marlane Barnes | Audrey |
| Allan Havey | Lou Avery |
| Craig Calman | SCDP Office Employee
(uncredited) |
| Christopher Hedrick | SCDP Associate
(uncredited) |
| Cary Huff | Sterling, Cooper Client
(uncredited) |
| Cheyenne Nugent | SC&P Secretary
(uncredited) |
| Hudson Phillips | SCDP Male
(uncredited) |
| Paul Mitchell Rosenblum | Dancer Fitzgerald Executive
(uncredited) |