| Dermot Crowley | DSU Martin Schenk |
| Idris Elba | DCI John Luther |
| Warren Brown | DS Justin Ripley |
| Rachel Hankey | Emily Hammond |
| Kevin Fuller | Paul Ellis |
| Nikki Amuka-Bird | DCI Erin Gray |
| David O'Hara | DSU George Stark |
| Michael Smiley | Benny Deadhead |
| Sienna Guillory | Mary Day |
| Shaun Mason | Sean 'Beanie' Beamish |
| Lucian Msamati | Ken Barnaby |
| Maria Miles | Tessa Barnaby |
| Sasha Behar | Dani Lane |
| Selva Rasalingam | Craig Lane |
| Lasco Atkins | Execution Spectator
(uncredited) |
| Paul Blackwell | Police Officer
(uncredited) |
| Richard Herdman | Uniform Police Officer
(uncredited) |
| Matthew David McCarthy | City Worker
(uncredited) |
| Vic Waghorn | Police Officer
(uncredited) |
| Glenn Webster | Paramedic
(uncredited) |