| Naveen Andrews | Sayid Jarrah |
| Nestor Carbonell | Richard Alpert
(credit only) |
| Henry Ian Cusick | Desmond Hume
(credit only) |
| Emilie de Ravin | Claire Littleton |
| Michael Emerson | Ben Linus
(credit only) |
| Jeff Fahey | Frank Lapidus
(credit only) |
| Matthew Fox | Dr. Jack Shephard |
| Jorge Garcia | Hugo 'Hurley' Reyes |
| Josh Holloway | James 'Sawyer' Ford
(credit only) |
| Daniel Dae Kim | Jin-Soo Kwon |
| Yunjin Kim | Sun-Hwa Kwon
(credit only) |
| Ken Leung | Miles Straume |
| Evangeline Lilly | Kate Austen |
| Terry O'Quinn | Man in Black |
| Zuleikha Robinson | Ilana Verdansky
(credit only) |
| Veronica Hamel | Margo Shephard |
| Dylan Minnette | David Shephard |
| Mark Pellegrino | Jacob |
| Hiroyuki Sanada | Dogen |
| Dayo Ade | Justin |
| Sean Kinerney | Dogen's Son |
| John Herkenrath | Talent Contest Judge
(uncredited) |