| Adewale Akinnuoye-Agbaje | Mr. Eko |
| Naveen Andrews | Sayid Jarrah
(credit only) |
| Emilie de Ravin | Claire Littleton |
| Matthew Fox | Dr. Jack Shephard |
| Jorge Garcia | Hugo 'Hurley' Reyes |
| Josh Holloway | James 'Sawyer' Ford |
| Daniel Dae Kim | Jin-Soo Kwon
(credit only) |
| Yunjin Kim | Sun-Hwa Kwon |
| Evangeline Lilly | Kate Austen |
| Dominic Monaghan | Charlie Pace
(credit only) |
| Terry O'Quinn | John Locke |
| Harold Perrineau | Michael Dawson
(credit only) |
| Michelle Rodriguez | Ana Lucia Cortez
(credit only) |
| Cynthia Watros | Libby Smith |
| Michael Emerson | Henry Gale |
| Mira Furlan | Danielle Rousseau |
| M.C. Gainey | Tom Friendly |
| William Mapother | Dr. Ethan Rom |
| Tania Raymonde | Alex Rousseau |
| William Blanchette | Aaron Littleton
(uncredited) |
| Madison | Vincent the Dog
(uncredited) |