| Dennis Farina | Detective Joe Fontana |
| Jesse L. Martin | Detective Ed Green |
| S. Epatha Merkerson | Lieutenant Anita Van Buren |
| Sam Waterston | E.A.D.A. Jack McCoy |
| Annie Parisse | A.D.A. Alexandra Borgia |
| Fred Thompson | D.A. Arthur Branch |
| Myra Lucretia Taylor | Lillie Sands |
| Stephanie Roth Haberle | Gloria Rhodes |
| Leslie Hendrix | M.E. Dr. Elizabeth Rodgers |
| Richard Brooks | Defense Attorney Paul Robinette |
| Lauren Klein | Trial Judge Carla Solomon |
| Karen Olivo | Isabella Perez |
| Miriam A. Hyman | Savannah Watson |
| Adepero Oduye | Traci Sands |
| Catrina Ganey | Doris Creppler |
| Jordan Leeds | Trial Judge Harold Gordon |
| Selenis Leyva | Detective Mariluz Rivera |
| Phyllis Bash | Louise |
| Heather Simms | Althea Sands |
| John Joseph Gallagher | Herb Carson |
| Steve Brady | Dr. Robert Horton |
| Alicia Roper | Claire Porterhouse |
| Terrence Bae | Ben |
| Haerry Kim | Chu Hu |
| Mike Santana | Paz |
| Matthew J. Cyrus | Calvin |
| Elijah J. Harris | Mohammed |
| Venida Evans | Foreperson |
| Kim Gambino | Lawson |
| Richard Hirschfeld | Assistant M.E. Brody |
| Hudson Cooper | Clerk |
| John Cariani | CSU Technician Julian Beck |
| Michael Ciminera | Donatti |
| Ellen Halper | Protester |
| Steven Zirnkilton | Narrator |