| Dennis Farina | Detective Joe Fontana |
| Jesse L. Martin | Detective Ed Green |
| S. Epatha Merkerson | Lieutenant Anita Van Buren |
| Sam Waterston | E.A.D.A. Jack McCoy |
| Elisabeth Röhm | A.D.A. Serena Southerlyn |
| Fred Thompson | D.A. Arthur Branch |
| David Chandler | Melvin Silverman |
| Richard Sheridan Willis | Neal Freedman |
| Al Sapienza | Pete Andretti |
| Jade Scott Yorker | Anthony 'Psycho' Harrison |
| Leslie Hendrix | M.E. Dr. Elizabeth Rodgers |
| Daryl Edwards | Shawn Foreman |
| Teagle F. Bougere | Attorney Nelson |
| Sean Nelson | Steven 'Four Strike' Foreman |
| Nan-Lynn Nelson | Janet Foreman |
| JoAnna Rhinehart | Nicole Caldwell |
| Marylou Mellace | Judge Antonia Mellon |
| John Cariani | CSU Technician Julian Beck |
| Merwin Goldsmith | Judge Ian Feist |
| Selenis Leyva | Detective Mariluz Rivera |
| Funda Duval | Club Manager |
| Carla Greene | Cece |
| Esau Pritchett | Parole Officer Leon Mooney |
| Carey Reilly | Detective Jenny Gant |
| Timothy Roselle | Gus |
| Ron Domingo | Detective Gonzales |
| Keith Powell | Mike |
| Tom Day | Detective #1 |
| Jeff Woods Garlin | Detective #2 |
| Chris Fischer | Detective #3 |
| Sean Phillips | Uniform #1 |
| Sam Kitchin | Uniform #2 |
| Gregory Weinberg | Court Clerk |
| Sheree Ladove-Kent | Jury Foreperson |
| Randy DeOrio | Court Reporter |
| Christopher Michael Gerrard | Rap Producer |
| Emiko Koizumi | EMT |
| Larry Russo | Detective |
| Kenny Shapiro | Camara Operator |
| Sonny Vellozzi | Reporter |
| Neil Dawson | Man #1 |
| Dave Dyshuk | Juror |
| Patrick Antonio Tracey | Ronald Caldwell |
| Steven Zirnkilton | Narrator |