| Richard Belzer | John Munch |
| Giancarlo Esposito | Mike Giardello |
| Peter Gerety | Stuart Gharty |
| Clark Johnson | Meldrick Lewis |
| Yaphet Kotto | Al Giardello |
| Toni Lewis | Terri Stivers |
| Michael Michele | Rene Sheppard |
| Kyle Secor | Tim Bayliss |
| Jon Seda | Paul Falsone |
| Callie Thorne | Laura Ballard |
| Benjamín Benítez | Eric |
| Tim Carr | Police Cadet |
| Gary D'Addario | Lt. Jasper |
| Dave Eveler | Police Cadet |
| Sheila Hennessey | Arlene McCusker |
| Jaki-Terry | Marletta Manley
(as Jaki Terry) |
| Chuck Jeffreys | Desmond Clements |
| Clayton LeBouef | Col. George Barnfather |
| Jeff Mandon | Off. Fred Hellriegel |
| Sandra Reaves-Phillips | Eunetta Bryce
(as Sandra Reeves-Phillips) |
| Corey Parker Robinson | Yates |
| Marco St. John | Bus Driver McCusker |
| Sean Whitesell | Dr. Eli Devilbiss |
| David L. Marston | Dave
(uncredited) |
| Tony Martin | (uncredited) |
| Karl Otter | Crime Lab Photographer
(uncredited) |
| Towanda Underdue | Rioter
(uncredited) |
| Sharon Ziman | Naomi
(uncredited) |