| Kyle Chandler | Eric Taylor |
| Connie Britton | Tami Taylor |
| Zach Gilford | Matt Saracen |
| Minka Kelly | Lyla Garrity |
| Taylor Kitsch | Tim Riggins |
| Adrianne Palicki | Tyra Collette |
| Jesse Plemons | Landry Clarke |
| Aimee Teegarden | Julie Taylor |
| Gaius Charles | Brian 'Smash' Williams |
| D.W. Moffett | Joe McCoy |
| Jeremy Sumpter | J.D. McCoy |
| Brad Leland | Buddy Garrity |
| Dana Wheeler-Nicholson | Angela Collette |
| Derek Phillips | Billy Riggins |
| Sinqua Walls | Jamarcus Hall |
| Liz Mikel | Corrina Williams |
| Blue Deckert | Mac McGill |
| Louanne Stephens | Grandma Saracen |
| Stacey Oristano | Mindy Collette |
| Libby Villari | Mayor Rodell |
| Brandon Smith | Vice Principal Trucks |
| Preston Flagg | Daryl |
| Tai Powell | Angelina |
| Jim Garrity | Dr. Rabinow |
| Chloë Evans | Jolene (as Chloe Jacobs) |
| Nellie Gonzalez | Reporter #2 |
| Meltron Kendrick | Reporter #3 |
| Drew Waters | Wade |
| David Cowgill | Slammin' Sammy |
| Deana Ricks | Second Teacher |
| Chris Olson | Bill Bollinger |
| Lana Dieterich | Third Teacher |
| C.C. Stinson | Emily Walker |
| Anthony Solomon | Charles |
| Jonathan Shaffer | Falcon |
| Brandy Singleton | Girl in Hallway |
| Eric Alfio | Panther Football Player #48
(uncredited) |
| Stacy Lynn Austin | Cheerleader
(uncredited) |
| Nathan Bayless | Flag Runner
(uncredited) |
| Kimberly Lynn Campbell | Stadium Fan
(uncredited) |
| Chris Caulier | Football Player
(uncredited) |
| Gene Cervenka | Seven Senoritas Patron
(uncredited) |
| Archie Fields | Panther Football Player
(uncredited) |
| Michael Gazin | Panther Football Player #31
(uncredited) |
| James Jensen | Panther Football Player #90
(uncredited) |
| Adam Madrigal | Panther Player #37
(uncredited) |
| Nieko Mann | Noannie Williams
(uncredited) |
| Whitney McCauley | Sheila Williams
(uncredited) |
| Michael Muenchow Rivera | Panther Football Player #35 /
Jock
(uncredited) |
| Mitchell Parrack | Seven Senoritas Dancer
(uncredited) |
| Mackenzie Reed | Cheerleader
(uncredited) |
| James P. Rice | Football Fan
(uncredited) |
| Charlie m Stewart | Panther Fan
(uncredited) |
| Jordan Strassner | Cheerleader
(uncredited) |
| Gary Teague | Teacher
(uncredited) |
| Janine Turner | Katie McCoy
(uncredited) |
| Jeff Whitaker | Panther Play #9
(uncredited) |
| Heath Young | Football fan
(uncredited) |