| Kyle Chandler | Eric Taylor |
| Connie Britton | Tami Taylor |
| Gaius Charles | Brian 'Smash' Williams |
| Zach Gilford | Matt Saracen |
| Minka Kelly | Lyla Garrity |
| Taylor Kitsch | Tim Riggins |
| Adrianne Palicki | Tyra Collette |
| Jesse Plemons | Landry Clarke |
| Scott Porter | Jason Street |
| Aimee Teegarden | Julie Taylor |
| Dana Wheeler-Nicholson | Angela Collette |
| Brett Cullen | Walt Riggins |
| Kevin Rankin | Herc |
| Aasha Davis | Waverly Grady |
| Brad Leland | Buddy Garrity |
| Blue Deckert | Mac McGill |
| Derek Phillips | Billy Riggins |
| Louanne Stephens | Mrs. Saracen |
| Liz Mikel | Corrina Williams |
| Whitney McCauley | Sheila |
| Nieko Mann | Noannie Williams
(as Brittany 'Nieko' Mann) |
| David Cowgill | Slammin' Sammy |
| D'Anthony Palms | Anton |
| Kendrick Jefferson | Baxter |
| James Powers | Bradley |
| Ryan Ciardo | Chuck Pierce |
| Will Johnson | Thomas
(as William Johnson) |
| Loomis Warren | Greer |
| Aundrus Poole | Reggie Seale |
| Tiffany Burgos | Cathleen |
| Andrea Block | Laurel |
| Victor Diaz | Joe Dover |
| Jacqueline Journey | Karen Stark
(as Jacqueline Renee) |
| Myrna Cabello | Real Estate Agent |
| Diane Perella | Mortgage Broker |
| Anastasia Coon | Mrs. Carroll |
| Cy Young | Mr. Utz |
| Ryan Boggus | White Student |
| Robert O. Boothby | Corey
(as Robert Boothby) |
| Michael Caschette | J.D. |
| Devon Saul | Kenji |
| Norm Lyduch | Norm |
| Michael Fries | Slattery |
| Michelle Brew | Deana - Rally Girl
(uncredited) |
| JenelleRae Cardenas | Student
(uncredited) |
| Archie Fields | Panther Football Player
(uncredited) |
| Pablo Flores | Panther Assistant Coach
(uncredited) |
| Jessica Layne | Sally
(uncredited) |
| Wil Pollard | Football Player
(uncredited) |
| Joshua Ryan | Greer - Football Player #12
(uncredited) |
| Violet Saenz-Arocha | Reporter
(uncredited) |
| Gary Teague | Parent
(uncredited) |
| Barney Welch | Counselor Barney
(uncredited) |
| Heath Young | Football fan
(uncredited) |