| Kyle Chandler | Eric Taylor |
| Connie Britton | Tami Taylor |
| Gaius Charles | Brian 'Smash' Williams |
| Zach Gilford | Matt Saracen |
| Minka Kelly | Lyla Garrity |
| Taylor Kitsch | Tim Riggins |
| Adrianne Palicki | Tyra Collette |
| Jesse Plemons | Landry Clarke
(credit only) |
| Scott Porter | Jason Street |
| Aimee Teegarden | Julie Taylor |
| Dana Wheeler-Nicholson | Angela Collette |
| Kevin Rankin | Herc |
| Brad Leland | Buddy Garrity |
| Blue Deckert | Mac McGill |
| Liz Mikel | Corrina Williams |
| Louanne Stephens | Mrs. Saracen |
| Brent Smiga | Henry Saracen |
| Merrilee McCommas | Pam Garrity |
| Stacey Oristano | Mindy Collette |
| Libby Villari | Mayor Lucy Rodell |
| Eleese Lester | Barbara Gentry |
| Derek Phillips | Billy Riggins |
| Nieko Mann | Noannie Williams
(as Brittany 'Nieko' Mann) |
| Steven Chester Prince | Booster Reg
(as Steve Prince) |
| David Cowgill | Slammin' Sammy |
| Dale Watson and His Lonestars | Party Band |
| Michelle Brew | Rally Girl
(uncredited) |
| Franky Coronado | Teacher
(uncredited) |
| Archie Fields | Panther Football Player
(uncredited) |
| Andie Haddad | Fan
(uncredited) |
| Christian Haddad | Fan
(uncredited) |
| Kate Krause | Tabby Garrity
(uncredited) |
| Rupert-Anthony Ortiz | Panther Football Player #70
(uncredited) |
| Kathryn Rawson | Applebee's Waitress
(uncredited) |
| Gary Teague | Teacher
(uncredited) |
| Joey Truty | Little Buddy Garrity
(uncredited) |
| Heath Young | Football fan
(uncredited) |