| Kyle Chandler | Eric Taylor |
| Connie Britton | Tami Taylor |
| Gaius Charles | Brian 'Smash' Williams |
| Zach Gilford | Matt Saracen |
| Minka Kelly | Lyla Garrity |
| Taylor Kitsch | Tim Riggins |
| Adrianne Palicki | Tyra Collette |
| Jesse Plemons | Landry Clarke |
| Scott Porter | Jason Street |
| Aimee Teegarden | Julie Taylor |
| Aasha Davis | Waverly Grady |
| Maggie Wheeler | Teacher |
| Rebecca McFarland | Susanne Derr |
| Brad Leland | Buddy Garrity |
| Blue Deckert | Mac McGill |
| Liz Mikel | Corrina Williams |
| Nieko Mann | Noannie Williams
(as Brittany 'Nieko' Mann) |
| Whitney McCauley | Sheila Williams |
| Katherine Willis | Joanne Street |
| Mark Nutter | Mitchell Street |
| Louanne Stephens | Mrs. Saracen |
| Sid Johnson | Reverend Grady
(as Pastor Sid Johnson) |
| Derek Phillips | Billy Riggins |
| James Powers | Bradley Cole |
| Merrilee McCommas | Pam Garrity |
| Mark Walters | Jeff Sable |
| Andrea Block | Colleen |
| Lainie Safady | Kennedy |
| Kristy Vaughan | Brittany Beck |
| Ken Webster | Ben Beck |
| GiGi Erneta | Mrs. Dunn |
| Ryan Lee | Jake Dunn |
| Timothy F. Crowley | Coach Crowley
(as Timothy Crowley) |
| Edward Herndon | Aaron |
| David Baugh | Dude #1 |
| John Newton | Dude #2 |
| Ra'shel Kendrick | Smashette Twin #1 |
| Ra'nel Kendrick | Smashette Twin #2 |
| Stacey Schwartz | Smash Fan #2 |
| C. Ladd LeBus | Cheerleading Marshall
(as Ladd LeBus) |
| Andi René Christensen | Student |
| D.J. Castillo | Athletic Trainer /
Student
(uncredited) |
| Franky Coronado | Teacher
(uncredited) |
| Archie Fields | Panther Football Player
(uncredited) |
| Spencer Greenwood | Football Team Manager
(uncredited) |
| Kate Krause | Tabby Garrity
(uncredited) |
| Katina Latrell | Cheerleader
(uncredited) |
| Brent McGregor | Kastor
(uncredited) |
| Rupert-Anthony Ortiz | Panther Football Player #70
(uncredited) |
| Barney Welch | Counselor Barney
(uncredited) |
| Heath Young | Football fan
(uncredited) |