| Kyle Chandler | Eric Taylor |
| Connie Britton | Tami Taylor |
| Gaius Charles | Brian 'Smash' Williams |
| Zach Gilford | Matt Saracen |
| Minka Kelly | Lyla Garrity |
| Taylor Kitsch | Tim Riggins |
| Adrianne Palicki | Tyra Collette |
| Jesse Plemons | Landry Clarke |
| Scott Porter | Jason Street |
| Aimee Teegarden | Julie Taylor |
| Mathew Greer | Coach Deeks |
| Matthew Greer | Coach Deeks |
| Libby Villari | Mayor Lucy Rodell |
| Louanne Stephens | Mrs. Saracen |
| Brad Leland | Buddy Garrity |
| Derek Phillips | Billy Riggins |
| Mark Nutter | Mitchell Street |
| Katherine Willis | Joanne Street |
| Merrilee McCommas | Pam Garrity |
| Cindy Creekmore | Missy Aubrey |
| Noble Chase Pack | Little Buddy Garrity
(as Noble Pack) |
| Kate Krause | Tabby Garrity |
| Brian D. Phelan | QB Coach |
| Dago Pates | David Matters |
| John Hambrick | Eddie McMannus |
| Orlando Storm Smart | Little QB |
| Daniel Abikasis | Football player
(uncredited) |
| Gene Bolton | Dillon Offensive Line Coach
(uncredited) |
| Mack Brown | Booster
(uncredited) |
| Jake Carter | Football Player
(uncredited) |
| Shawn Cauthen | Dillon Football Player
(uncredited) |
| Erik Collins | News Crew
(uncredited) |
| Gina Garza | Student
(uncredited) |
| Eric Hack | Football Player
(uncredited) |
| Matthew T. Johnston | Assistant Coach
(uncredited) |
| Linda Klein | Nurse
(uncredited) |
| Matt Leonard | Football Player
(uncredited) |
| Scott Lilly | Trainer
(uncredited) |
| Robert E. Martinez | Football Team Manager
(uncredited) |
| Robin Maxkii | Pep Rally Girl
(uncredited) |
| John D. Montoya | (uncredited) |
| Dan Murphy | Sideline Football Fan
(uncredited) |
| Aerik E. Pachicano | Yearbook Photographer
(uncredited) |
| Jessie Pavelka | Team Captain
(uncredited) |
| Darryl K. Phipps | Football Player
(uncredited) |
| Robin Prough | Cheerleader
(uncredited) |
| Deana Ricks | Booster
(uncredited) |
| Shannon Joy Rodgers | Student Trainer
(uncredited) |
| Isaac Rodriguez | Reporter /
Diner Customer
(uncredited) |
| Nicole Taylor | Pretty Girl
(uncredited) |
| Gary Teague | Dillon Panther Football Fan
(uncredited) |
| Larry Ulrich | Head Trainer
(uncredited) |
| Angela Ware | (uncredited) |
| Heath Young | Football fan
(uncredited) |