| Neil Patrick Harris | Count Olaf |
| Patrick Warburton | Lemony Snicket |
| Malina Weissman | Violet Baudelaire |
| Louis Hynes | Klaus Baudelaire |
| K. Todd Freeman | Arthur Poe |
| Presley Smith | Sunny Baudelaire |
| Avi Lake | Isadora Quagmire |
| Dylan Kingwell | Duncan Quagmire |
| Sara Rue | Olivia Caliban |
| Roger Bart | Vice Principal Nero |
| Nathan Fillion | Jacques Snicket |
| Patrick Breen | Larry Your-Waiter |
| Kitana Turnbull | Carmelita Spats |
| Usman Ally | Hook-Handed Man |
| Matty Cardarople | Henchperson of Indeterminate Gender |
| Sara Canning | Jacquelyn |
| John DeSantis | Bald Man |
| Jacqueline Robbins | White Faced Woman #1 |
| Joyce Robbins | White Faced Woman #2 |
| Malcolm Stewart | Mr. Remora |
| BJ Harrison | Mrs. Bass |
| Tara Strong | Sunny |
| Bronwen Smith | Miss Tench |
| Kwasi Thomas | Bus Driver |
| Chase Nicholson | Unfortunate Student |
| Yasmeene Ball | Carmelita's Lackey #1 |
| Emily Delahunty | Carmelita's Lackey #2 |
| Barry Sonnenfeld | Mr. Tamerlane |
| Rhys Darby | Charles |
| Rita Hodson | Teacher |
| Maestro Porus Irani | School Teacher |
| Aasif Mandvi | Dr. Montgomery Montgomery |
| Esabella Anna Karena Strickland | School Girl |
| Alfre Woodard | Aunt Josephine Anwhistle |