| James Gandolfini | Tony Soprano |
| Lorraine Bracco | Dr. Jennifer Melfi |
| Edie Falco | Carmela Soprano |
| Michael Imperioli | Christopher Moltisanti |
| Dominic Chianese | Junior Soprano |
| Tony Sirico | Paulie 'Walnuts' Gualtieri |
| Robert Iler | A.J. Soprano |
| Jamie-Lynn Sigler | Meadow Soprano |
| Drea de Matteo | Adriana La Cerva |
| Aida Turturro | Janice Soprano |
| John Ventimiglia | Artie Bucco |
| Steve Schirripa | Bobby 'Bacala' Baccalieri
(as Steven R. Schirripa) |
| Robert Funaro | Eugene Pontecorvo |
| Kathrine Narducci | Charmaine Bucco
(as Katherine Narducci) |
| Joe Pantoliano | Ralph Cifaretto |
| Burt Young | Bobby 'Bacala' Sr. |
| Peter Riegert | Assemblyman Zellman |
| Richard Portnow | Attorney Melvoin |
| Tom Aldredge | Hugh DeAngelis |
| Suzanne Shepherd | Mary DeAngelis |
| Brian Tarantina | Mustang Sally |
| Jason Cerbone | Jackie Aprile Jr. |
| Vincent Curatola | Johnny Sack |
| John Fiore | Gigi Cestone |
| Joseph R. Gannascoli | Vito Spatafore |
| Frank Pellegrino | Frank Cubitosi |
| Paul Schulze | Father Phil Intintola |
| Matt Servitto | Agent Dwight Harris |
| Marie Donato | 2 to 5 /
7 to 9 |
| Gary Evans | FBI Tech #1 |
| Vanessa Ferlito | Tina |
| Sheila Gibbs | Receptionist |
| Glenn Kessler | FBI Tech #2 |
| Michael Matera | Carlos
(as Michael Martochio) |
| Vincent J. Orofino | Bryan Spatafore
(as Vinnie Orofino) |
| Sheelagh Tellerday | Woman |
| Michael Variano | Petey |
| Erik Weiner | Manager |
| Charles S. Dutton | Officer Wilmore |
| Peter Austin Noto | Tony's Friend
(uncredited) |
| David Ojalvo | Vesuvio Patron
(uncredited) |