| James Gandolfini | Tony Soprano |
| Lorraine Bracco | Dr. Jennifer Melfi |
| Edie Falco | Carmela Soprano |
| Michael Imperioli | Christopher Moltisanti |
| Dominic Chianese | Junior Soprano |
| Vincent Pastore | Salvatore 'Big Pussy' Bonpensiero |
| Steven Van Zandt | Silvio Dante |
| Tony Sirico | Paulie 'Walnuts' Gualtieri |
| Robert Iler | A.J. Soprano |
| Drea de Matteo | Adriana La Cerva |
| David Proval | Richie Aprile |
| Aida Turturro | Janice Soprano |
| Jerry Adler | Hesh Rabkin |
| Kathrine Narducci | Charmaine Bucco
(as Katherine Narducci) |
| John Ventimiglia | Artie Bucco |
| Peter Bogdanovich | Dr. Elliot Kupferberg |
| Linda Emond | Dahlia |
| Louis Lombardi | Skip Lipari |
| Oksana Lada | Irina Peltsin
(as Oksana Babiy) |
| Federico Castelluccio | Furio Giunta |
| Vincent Curatola | Johnny 'Sack' Sacramoni |
| Steve Schirripa | Bobby 'Bacala' Baccalieri
(as Steven R. Schirripa) |
| John Fiore | Gigi Cestone |
| Stephen Payne | Dominic |
| Lydia Gaston | Rosie |
| Sasha Nesterov | Russian Man |
| Elena Antonenko | Russian Woman |
| Oni Faida Lampley | Cynthia |
| Scott Lucy | Acting Student |
| Ajay Naidu | Omar |
| Robert Prescott | Mitch |
| Phyllis Somerville | Brenda |
| Todd Carroll | Acting Student
(uncredited) |
| Katalin Pota | Lilliana
(uncredited) |