| Michael C. Hall | Dexter Morgan |
| Julie Benz | Rita Bennett |
| Jennifer Carpenter | Debra Morgan |
| Erik King | Sgt. James Doakes |
| Luna Lauren Velez | Lt. Maria LaGuerta
(as Lauren Velez) |
| David Zayas | Det. Angel Batista |
| James Remar | Harry Morgan
(credit only) |
| Geoff Pierson | Capt. Tom Matthews |
| C.S. Lee | Vince Masuka |
| Mark Pellegrino | Paul Bennett |
| Christian Camargo | Rudy Cooper |
| Margo Martindale | Camilla |
| Martinez Evelina | Monique
(as Tomiko Martinez) |
| Angela Alvarado | Nina Batista
(as Angela Alvarado Rosa) |
| Debbie Lee Carrington | Patty |
| Christina Robinson | Astor Bennett |
| Daniel Goldman | Cody Bennett |
| Romeo Brown | Andy |
| Teddy Lane Jr. | Jerry |
| Kevin Thompson | Male Elf |
| Francisco Viana | Det. Jake Simms |
| Maite Schwartz | Reporter |
| Amanda Tepe | Young Lab Tech |
| Erica Luttrell | Library Aide |
| Bruce Holman | Det. Michael Soderquist
(uncredited) |
| Jonathan Khan | Off. Wong
(uncredited) |
| Chris Krauser | F.B.I Special Task Force Agent
(uncredited) |
| Nikki Magnusson | Beach Jogger
(uncredited) |
| Sandra Medina | Club Goer
(uncredited) |
| Mark Anthony Williams | Forensic Tech
(uncredited) |
| Raymond T. Williams | Extra
(uncredited) |