| Roger Allam | DI Fred Thursday |
| Louis Ashbourne Serkis | Tommy Cork |
| Andrew Gower | Nicholas Myers |
| Oliver Lansley | Benny Topling |
| Martin Hancock | 'Nosey' Parker |
| Oliver Coleman | Henry Portmore |
| Sarah Beck Mather | Hilary Portmore |
| Shaun Evans | DC Endeavour Morse |
| Nick Waring | Force Medical Examiner |
| Mark Flitton | Prison Officer Wainwright |
| Derek Hutchinson | Chief Constable Rupert Standish |
| Richard Dixon | Josiah Landesman |
| Anton Lesser | Chief Superintendent Reginald Bright |
| Abigail Thaw | Dorothea Frazil |
| Gordon Kennedy | Alderman Gerald Wintergreen |
| Sarah Woodward | Hazel Wintergreen |
| James Wilby | ACC Clive Deare |
| Emma Hiddleston | Angela McGarrett |
| Sean Rigby | PC Jim Strange |
| Sara Vickers | Joan Thursday |
| Caroline O'Neill | Win Thursday |
| Jack Bannon | Sam Thursday |
| Abby Ford | Mona Cork |
| Jack Laskey | DS Peter Jakes |
| James Bradshaw | Dr. Max DeBryn |
| Shvorne Marks | Monica Hicks |
| Vince Leigh | DI Hugh Chard |
| Paul Ridley | Dr. Jasper Fairbridge |
| Simon Kunz | DI Bart Church |
| George Turvey | PC Willis |
| Max Gold | DI Gregson |
| Lasco Atkins | Rocker |
| Colin Dexter | Gentleman on Bench at College |
| Steve Munroe | Police Officer |