| Jessica Alba | Max Guevera |
| Michael Weatherly | Logan Cale |
| Jensen Ackles | Alec |
| Martin Cummins | Ames White |
| Kevin Durand | Joshua |
| Richard Gunn | Calvin 'Sketchy' Theodore |
| J.C. MacKenzie | Reagan 'Normal' Ronald |
| Valarie Rae Miller | Cynthia 'Original Cindy' McEachin |
| John Savage | Donald Lydecker |
| Rob LaBelle | Engel - Manticore Scientist |
| Ashley Scott | Asha Barlow |
| Janet Wright | Annie |
| Shawn Stewart | Bloody Fighter 1 |
| Ken Kirzinger | Bloody Fighter 2 |
| John DeSantis | The Mangler - Miller |
| Brendan Beiser | Blue Collar Husband |
| Jane Sowerby | Blue Collar Wife |
| Kyle Alisharan | Operative |
| John Hainsworth | Skinny Homeless Guy |
| Kimani Ray Smith | Bearded Homeless Guy |
| Deb Macatumpag | She-Beast |
| Vincent Walker | Guy with Shotgun |
| Nicholas Harrison | Cop 1 |
| Angela Uyeda | Cop 2 |
| Ryan DeBoer | X6-252 |
| Stephen Aberle | Professor Long |
| Brittany Cuevas | Young Max - 6 years |
| Norman Armour | A Young Sandeman |
| Shekhar Paleja | Trooper |