| Joe Mantegna | David Rossi |
| Paget Brewster | Emily Prentiss |
| Shemar Moore | Derek Morgan |
| Matthew Gray Gubler | Dr. Spencer Reid |
| Kirsten Vangsness | Penelope Garcia |
| Thomas Gibson | Aaron Hotchner |
| Brad William Henke | Steven |
| Matthew Glave | Detective Bailey |
| Stacey Oristano | Anisa Gold |
| Roberta Valderrama | Bernice |
| Timothy V. Murphy | Ian Doyle |
| Gray Stevenson | Linda Dean |
| Eric Ramey | Dr. Samuel Bayo |
| Nicolas Pajon | ND Agent |
| Ryan Christiansen | Uniform |
| Vahe Bejan | Taxi Driver |
| Logan Holladay | Biker |
| Salem the Cat | Prentiss's Cat
(uncredited) |
| Kimberly Fowler | Taxi passenger
(uncredited) |
| Norma J. Houser | Pedestrian Couple Walking
(uncredited) |
| Angus Macfadyen | Sean McAllister
(uncredited) |
| Jay Murray | Pedestrian Couple Walking
(uncredited) |
| Uwe Schwarzwalder | French Officer
(uncredited) |
| Stephan Todd | Officer Hall
(uncredited) |