| Mandy Patinkin | Jason Gideon |
| Thomas Gibson | Aaron Hotchner |
| Lola Glaudini | Elle Greenaway |
| Shemar Moore | Derek Morgan |
| Matthew Gray Gubler | Dr. Spencer Reid |
| A.J. Cook | Jennifer Jareau |
| Kirk B.R. Woller | Franklin Graney |
| Daniel Zacapa | Captain Griffith |
| Keith Diamond | Detective Cornelius Martin |
| Kirsten Vangsness | Penelope Garcia |
| Patty McCormack | Marcia Gordon |
| Kelley West | Shelly Hart |
| McKerrin Kelly | Brenda Samms |
| Albert Malafronte | Bill Gordon |
| Ron Roggé | San Diego Patrolman |
| Brian Appel | Clerical Agent |
| Sunkrish Bala | Jordan the Receptionist |
| Teri Ann Krefting | Video Aerobics Instructor |
| James Bannon | V
(uncredited) |
| Brevard Hudson | FBI Crime Scene Investigator
(uncredited) |