| Zachary Levi | Chuck Bartowski |
| Yvonne Strahovski | Sarah Walker |
| Joshua Gomez | Morgan Grimes |
| Ryan McPartlin | Devon 'Captain Awesome' Woodcomb |
| Mark Christopher Lawrence | Big Mike |
| Vik Sahay | Lester Patel |
| Scott Krinsky | Jeff Barnes |
| Bonita Friedericy | General Diane Beckman |
| Sarah Lancaster | Ellie Bartowski |
| Adam Baldwin | John Casey |
| Eric Roberts | Packard |
| Dave Bautista | T.I. |
| Mekenna Melvin | Alex McHugh |
| Joel David Moore | Mackintosh |
| Koby Azarly | Iranian sgt |
| Linda Hamilton | Mary Bartowski |
| Julie McKinnon | Buy More Customer |
| Mariano 'Big Dawg' Mendoza | David Bautista PD |
| Joshua Rush | Young Chuck |
| Omid Zader | Iranian soldier #2 |