| Nathan Fillion | Richard Castle |
| Stana Katic | Kate Beckett |
| Susan Sullivan | Martha Rodgers |
| Jon Huertas | Javier Esposito |
| Seamus Dever | Kevin Ryan |
| Tamala Jones | Lanie Parish |
| Molly C. Quinn | Alexis Castle
(credit only) |
| Penny Johnson Jerald | Captain Victoria Gates
(credit only) |
| Gregory Harrison | Danny Valentine |
| Jaleel White | Mickey Franks |
| James Eckhouse | Gene Vogel |
| Joy Osmanski | Liz Bell |
| Mark Rolston | Kurt Van Zant |
| Dustin Ingram | Chad |
| Eden Malyn | Tina Tamino |
| Joey Honsa | Sid's Wife |
| Carly Rae Jepsen | Carly Rae Jepsen |
| Christine Scott Bennett | Karin |
| Keenan Henson | Rob |
| Mike Kalinowski | Patrick |
| Janice Kent | Evelyn Ross |
| Janet Ratiu | Detective |
| Stacie Theon | Stage Manager |
| Bob Brauer | SNT Employee
(uncredited) |
| Toni French | Audience
(uncredited) |