| Nathan Fillion | Richard Castle |
| Stana Katic | Kate Beckett |
| Susan Sullivan | Martha Rodgers |
| Jon Huertas | Javier Esposito |
| Seamus Dever | Kevin Ryan |
| Tamala Jones | Lanie Parish |
| Molly C. Quinn | Alexis Castle
(as Molly Quinn) |
| Penny Johnson Jerald | Captain Victoria Gates |
| Geoff Pierson | Mr. Smith |
| Derek Webster | Mayor Robert Weldon |
| Adam Kulbersh | Brian Shay |
| Michael Grant Terry | Jordan Norris |
| Rebecca Field | Marilyn Kane |
| Germaine De Leon | Edgar Navarro |
| Steven Brand | Trevor Haynes |
| Cara Pifko | Roberta Cambridge |
| Dave Florek | Harvey |
| Victoria Gabrielle Platt | Connie Park
(as Victoria Platt) |
| Mimi Michaels | Sarah Marx |
| Patrick Cohen | Patrick McConnell |
| D.C. Douglas | Bill Moss |
| Susan Spano | Kitty |
| Tracy Scoggins | Lana |
| Tara Platt | Janelle |
| Cecelia Specht | Jolene /
Screaming D.A.G. Operator |
| Deanna Tryon | Mayor's Wife
(uncredited) |