| Nathan Fillion | Richard Castle |
| Stana Katic | Kate Beckett |
| Susan Sullivan | Martha Rodgers |
| Jon Huertas | Javier Esposito |
| Seamus Dever | Kevin Ryan |
| Tamala Jones | Lanie Parish |
| Molly C. Quinn | Alexis Castle
(as Molly Quinn) |
| Penny Johnson Jerald | Captain Victoria Gates
(credit only) |
| Fredric Lehne | Addison Smith |
| Amanda Walsh | Lulu, Jack's Producer |
| Vernee Watson | Mercy LaGrande /
Mercedes King
(as Vernée Watson) |
| Mark Harelik | Pete Benton |
| Juliana Dever | Jenny Duffy-O'Malley |
| Vincent Guastaferro | Steve Fuller |
| Joel Stoffer | Ron Berger |
| Shawn Carter Peterson | Barry Bavetta |
| Philipp Karner | Jack Sinclair |
| Christian S. Anderson | Harry Boyer
(as Christian Anderson) |
| Jennifer Cortese | Margaret Boyer |
| Josh Hopkins | Officer
(uncredited) |