| Jason Bateman | Michael Bluth |
| Portia de Rossi | Lindsay Bluth Fünke |
| Will Arnett | Gob Bluth |
| Michael Cera | George-Michael Bluth |
| Alia Shawkat | Maeby Fünke |
| Tony Hale | Buster Bluth |
| David Cross | Tobias Fünke |
| Jeffrey Tambor | George Bluth Sr. /
Oscar Bluth |
| Jessica Walter | Lucille Bluth |
| Zach Braff | Phillip Litt |
| Dick Van Patten | Cal Cullen |
| Jeff Garlin | Mort Meyers |
| Dave Attell | Self |
| Judy Greer | Kitty Sanchez |
| Rene Millan | Waiter |
| Michael Malota | College Kid #1 |
| Matt McKane | College Kid #2
(as Matthew McKane) |
| Beau Wirick | College Kid #3 |
| Agustin Bunuel | Construction Worker
(uncredited) |
| Joe Damian Daly | Spring Breaker
(uncredited) |
| Jillian Difusco | Protestor
(uncredited) |
| Shannon Factor | Self
(uncredited) |
| Ron Howard | Narrator
(voice) (uncredited) |
| John McCook | "Scandal Makers" Narrator
(voice) (uncredited) |
| Sarah Scott | 'Beautiful' Kitty
(uncredited) |