| Sarah Paulson | Linda Tripp |
| Beanie Feldstein | Monica Lewinsky |
| Annaleigh Ashford | Paula Jones |
| Margo Martindale | Lucianne Goldberg |
| Edie Falco | Hillary Clinton |
| Clive Owen | William Jefferson Clinton |
| Colin Hanks | Mike Emmick |
| Mira Sorvino | Marcia Lewis |
| Dan Bakkedahl | Judge Kenneth Starr |
| Darren Goldstein | Jackie Bennett |
| Rae Dawn Chong | Betty Currie |
| Taran Killam | Steve Jones |
| Ashlie Atkinson | Juanita Broaddrick |
| Scott Michael Morgan | Mike McCurry |
| Patrick Fischler | Sidney Blumenthal |
| Joseph Mazzello | Paul Begala |
| Lindsey Broad | Karin Immergut |
| Christopher Redman | Anthony Zaccagnini |
| Judith Light | Susan Carpenter-McMillan |
| Craig Welzbacher | Agent Irons |
| Brian Maillard | Special Fallon |
| Emma Malouff | Allison Tripp |
| Tom Simmons | Willie |
| Jenny C. Paul | Susan |
| Jim Rash | Ken Bacon |
| Ryan Nassif | Ryan Tripp |
| Jamie Baer | Colleen |
| Jared Gertner | Sol Wisenberg |
| Alan Starzinski | Brett Kavanaugh |
| Monique Mosee | Ken Bacon's Secretary |
| Warren Sweeney | Plato Cacheris |
| Ira Scipio | FBI Agent |
| Cat Elliott | Reporter Outside of Courthouse #1 |
| LaSaundra Gibson | Reporter Outside of Courthouse #2 |
| William Sterling | Reporter Outside of Courthouse #3 |
| Bamm Ericsen | Street Preacher |
| Glenn Edwards | CNN Interviewer |
| Cheryl Francis Harrington | Perplexed Woman |
| Zachary Margulies | Aide |
| B Z Cullins | Court Security Officer |
| Taneka Johnson | Forewoman Freda Alexander |
| Jim Garrity | Jim Moran |
| Suzanne H. Smart | Juror Who Looks Like Kirstie Alley |
| Richard Wharton | Ponytail Juror |
| Celestial | Elderly Female Juror |
| Pamela Roberts | Woman in Burgundy |
| Brandee Steger | Meticulous Juror |
| Chanda Hartman | Juror in Earth Tones |
| Scott Mosenson | Dr. Loeb |
| Charlotte Flyte | Wincing Reporter |
| Aaron Coleman | Nathaniel Speights |
| Vick Sabian | Ron (Groundskeeper) |
| Jason C. Daniels | Residence Inn Dad |
| Ethan Hathaway | Residence Inn Son |
| Nicholas Dubberley | Residence Inn Man |
| Mary Kate Corsetti | Reporter Outside of Courthouse #4 |
| Don Frankel | Accordian Player #1 |
| Daniel Avidon | Accordian Player #2 |
| Christina Miller | Grand Juror #23 |