| Dominic West | Off. James 'Jimmy' McNulty |
| John Doman | Dep. Comm. for Operations William A. Rawls |
| Frankie Faison | Commissioner Ervin H. Burrell |
| Aidan Gillen | Councilman Thomas 'Tommy' Carcetti |
| Deirdre Lovejoy | Asst. State's Atty. Rhonda Pearlman |
| Clarke Peters | Det. Lester Freamon |
| Wendell Pierce | Det. William 'Bunk' Moreland |
| Lance Reddick | Maj. Cedric Daniels |
| Andre Royo | Reginald 'Bubbles' Cousins |
| Sonja Sohn | Det. Shakima 'Kima' Greggs |
| Jim True-Frost | Roland 'Prez' Pryzbylewski |
| Robert Wisdom | Howard 'Bunny' Colvin |
| Seth Gilliam | Sgt. Ellis Carver |
| Domenick Lombardozzi | Sgt. Thomas 'Herc' Hauk |
| Reg E. Cathey | Norman Wilson |
| Chad L. Coleman | Dennis 'Cutty' Wise |
| Jamie Hector | Marlo Stanfield |
| Glynn Turman | Mayor Clarence V. Royce |
| J.D. Williams | Preston 'Bodie' Broadus |
| Michael Kenneth Williams | Omar Little |
| Corey Parker Robinson | Det. Leander Sydnor |
| Isiah Whitlock Jr. | State Sen. R. Clayton 'Clay' Davis |
| Jermaine Crawford | Duquan 'Dukie' Weems |
| Maestro Harrell | Randy Wagstaff |
| Julito McCullum | Namond Brice |
| Tristan Mack Wilds | Michael Lee |
| Gbenga Akinnagbe | Chris Partlow |
| Hassan Johnson | Roland 'Wee-Bey' Brice |
| Megan Anderson | Jen Carcetti |
| Susan Duvall | Assistant Principal Marcia Donnelly |
| Michael Hyatt | Brianna Barksdale |
| Jay Landsman | Lt. Dennis Mello |
| Edward T. Norris | Det. Edward Norris |
| Delaney Williams | Sgt. Jay Landsman |
| Marlyne Barrett | Council President Nerese Campbell |
| Brandy Burre | Theresa D'Agostino |
| Dravon James | Grace Sampson |
| Karen Vicks | Gerry |
| Christopher Mann | Councilman Anthony 'Tony' Gray |
| Frederick Strother | State Delegate Odell Watkins |
| Frank Reid | Reverend |
| Melvin Williams | Deacon |
| Tevin Brown | Man |
| Nathan Corbett | Donut |
| Thuliso Dingwall | Kenard |
| Denise Hart | Miss Anna Jeffries |
| Sandi McCree | De'Londa Brice |
| Jonnie Brown | Off. Eddie Walker |
| Benjamin Busch | Off. Anthony Colicchio |
| Michael Salconi | Off. Michael 'Sanny' Santangelo |
| Brian Anthony Wilson | Det. Vernon Holley |
| Queen Nzinga Ama Linton | Female Rail Passenger |
| Isis McCray | Tiff |
| Felicia Pearson | Felicia 'Snoop' Pearson |
| Jack Seeley | Bigoted Voter |
| Gregory L. Williams | Det. Michael Crutchfield |
| Michael Ahl | Detective |
| Larry Andrews | Donnie |
| Demetria Bailey | Perlene Scott |
| Tyrell Baker | Little Kevin |
| Nora Bauer | Business Traveler |
| Christopher Carver | Mayor Royce's Aide |
| Michael Coley | Kwame |
| Dan De Luca | David Parenti |
| Brian Dragonuk | Bar Patron |
| Alexander Emmert | Asst. D.A. Becker |
| Tyreeka Freamon | Middle School Clerk |
| Ernest Glover | Poll Worker |
| Edward Bernard Green Jr. | Spider |
| Na'Dria Jennings | Chandra Porter |
| Taylor King | Zenobia Dawson |
| Jeffrey Lorenzo | Karim Williams |
| Susan Lynskey | Lip Reader |
| E Marshall | Voter |
| David L. Marston | Voter |
| S. Robert Morgan | Butchie |
| Kwame Patterson | 'Monk' Metcalf |
| Derrick Purvey | Big Guy |
| Kelly Anne Rohde | Election Poller |
| Tony Ruggieri | Amtrak Police Supervisor |
| Ryan Sands | Off. Lloyd 'Truck' Garrick |
| Darrell M. Smith | School Officer Turner |
| Diana Villamonte | Rachel Shapiro |
| Jason Wharton | Albert Stokes |