Dominic West | Off. James 'Jimmy' McNulty |
Chris Bauer | Frank Sobotka |
Paul Ben-Victor | Spiros 'Vondas' Vondopoulos |
John Doman | Col. William A. Rawls |
Idris Elba | Russell 'Stringer' Bell |
Wood Harris | Avon Barksdale |
Deirdre Lovejoy | Asst. State's Atty. Rhonda Pearlman |
Clarke Peters | Det. Lester Freamon |
Wendell Pierce | Det. William 'Bunk' Moreland |
Lance Reddick | Lt. Cedric Daniels |
Andre Royo | Reginald 'Bubbles' Cousins |
Amy Ryan | Off. Beatrice 'Beadie' Russell |
Sonja Sohn | Det. Shakima 'Kima' Greggs |
Seth Gilliam | Sgt. Ellis Carver |
Domenick Lombardozzi | Det. Thomas 'Herc' Hauk |
Jim True-Frost | Det. Roland 'Prez' Pryzbylewski |
James Ransone | Chester 'Ziggy' Sobotka |
Pablo Schreiber | Nick Sobotka |
Method Man | Melvin 'Cheese' Wagstaff |
Melanie Nicholls-King | Cheryl |
Michael Potts | Brother Mouzone |
Bill Raymond | The Greek |
Al Brown | Maj. Stanislaus Valchek |
Robert F. Chew | Joseph 'Proposition Joe' Stewart |
Kristin Proctor | Aimee |
Merritt Wever | Prissy |
Benay Berger | FBI Supervisor Amanda Reese |
Toni Lewis | F.B.I. Agent |
Tom Mardirosian | Agent Kristos Koutris |
Delaney Williams | Sgt. Jay Landsman |
Teddy Cañez | George 'Double G' Glekas |
Jeffrey Fugitt | Claude Diggins |
Lev Gorn | Eton Ben-Eleazer |
Charley Scalies | Thomas 'Horseface' Pakusa |
J.D. Williams | Preston 'Bodie' Broadus |
Chris Ashworth | Sergei 'Serge' Malatov |
Kevin McKelvey | F.B.I. Agent |
S. Robert Morgan | Butchie |
Doug Olear | FBI Spec. Agent Terrance 'Fitz' Fitzhugh |
William L. Thomas | FBI Special Agent Mason |
Richard Burton | Sean 'Shamrock' McGinty |
Luray Cooper | Nathaniel 'Nat' Coxson |
Jeffrey Pratt Gordon | John 'Johnny Fifty' Spamanto |
Tommy Hahn | FBI Special Agent Salmond |
De'Rodd Hearns | Herbert De'Rodd 'Puddin' Johnson |
Bus Howard | Vernon 'Ott' Motley |
Wes Johnson | Security Supervisor |
DeAndre McCullough | Lamar |
Oleg Prudius | Henchman |
Donald Rey | Copy Shop Employee |
Leo Rogstad | Russian Mope |
Michael Kenneth Williams | Omar Little |