| Stockard Channing | Abbey Bartlet |
| Dulé Hill | Charlie Young |
| Allison Janney | C.J. Cregg |
| Joshua Malina | Will Bailey |
| Janel Moloney | Donna Moss |
| Richard Schiff | Toby Ziegler |
| John Spencer | Leo McGarry |
| Bradley Whitford | Josh Lyman |
| Martin Sheen | President Josiah Bartlet |
| Timothy Busfield | Danny Concannon |
| John Amos | Percy Fitzwallace |
| Lily Tomlin | Deborah Fiderer |
| Nina Siemaszko | Ellie Bartlet |
| Anna Deavere Smith | Nancy McNally |
| Annabeth Gish | Elizabeth Bartlet Westin |
| Clark Gregg | FBI Special Agent Michael Casper |
| Geoff Pierson | Senate Minority Leader Tripplehorn |
| Zeljko Ivanek | Steve Atwood |
| Steven Eckholdt | Doug Westin |
| NiCole Robinson | Margaret Hooper |
| Charlotte Colavin | Representative Sheila Fields |
| Thomas Kopache | Assistant Secretary of State Bob Slatterly |
| Bennet Guillory | Rep. Jackson |
| Melissa Fitzgerald | Carol Fitzpatrick |
| Kim Webster | Ginger |
| Peter James Smith | Ed |
| William Duffy | Larry |
| Richard Whiten | Winston |
| Timothy Davis-Reed | Mark O'Donnell |
| Charles Noland | Reporter Steve |
| Mindy Seeger | Chris |
| John Colella | Reporter 2 |
| Hira Ambrosino | Reporter 3 |
| Ivan Allen | News Anchor Roger Salier |
| Stephen Alexander | Secret Service Agent Pitt |
| Jerry Buys | Secret Service Agent |
| John Goodman | Glenallen Walken |
| Ralph Kampshoff | Rear Admiral Payne |
| Aaron Michael Lacey | Secret Service Agent |
| Lizz Robbins | Mourner |
| Natasha Sattler | Teen Well Wisher |