| Rob Lowe | Sam Seaborn
(credit only) |
| Dulé Hill | Charlie Young |
| Allison Janney | C.J. Cregg |
| Joshua Malina | Will Bailey |
| Janel Moloney | Donna Moss |
| Richard Schiff | Toby Ziegler |
| John Spencer | Leo McGarry |
| Bradley Whitford | Josh Lyman |
| Martin Sheen | President Josiah Bartlet |
| Timothy Busfield | Danny Concannon |
| Granville Van Dusen | Assistant Secretary of State for Public Affairs Bryce Lilly |
| Danica McKellar | Elsie Snuffin |
| Steve Ryan | Secretary of Defense Miles Hutchinson |
| Victor McCay | Peter |
| Thomas Kopache | Assistant Secretary of State Bob Slatterly |
| Gibby Brand | Adam Kent |
| Faran Tahir | Manny |
| John Cothran | Civilian Advisor
(as John Cothran Jr.) |
| Melissa Fitzgerald | Carol Fitzpatrick |
| Peter James Smith | Ed |
| William Duffy | Larry |
| Devika Parikh | Bonnie |
| Kris Murphy | Katie Witt |
| Timothy Davis-Reed | Mark O'Donnell |
| Abdoulaye NGom | Archbishop Zake Kintaka
(as Abdoulaye N'Gom) |
| Paul Kent | Cardinal |
| Mark Chaet | Imam |
| Ralph Meyering Jr. | Director #2 |
| Dan Gerrity | Director #3 |
| Nicole Lyn | Intern Stacy |
| Joel Anderson | Civilian #1 |
| Geoffrey Ewing | Senator Beckwith |
| Dan Ziskie | O'Donnell
(as Daniel Ziskie) |
| Timothy Rice | Chief Justice |
| Edward Beckford | Secret Service Agent
(uncredited) |
| Jerry Buys | Secret Service Agent
(uncredited) |
| Michael Leydon Campbell | (uncredited) |
| Brian Dragonuk | Presidential Aide with Football
(uncredited) |
| Abazar Khayami | Agent 101
(uncredited) |
| Aaron Michael Lacey | US Capitol Police
(uncredited) |
| Christopher H. Myers | Graduating Student
(uncredited) |
| Timothy J. Scanlin Jr. | Secret Service Agent
(uncredited) |
| Eddy Shalita | Patron
(uncredited) |
| Towanda Underdue | Ball Attendee
(uncredited) |