| Rob Lowe | Sam Seaborn |
| Dulé Hill | Charlie Young |
| Allison Janney | C.J. Cregg |
| Janel Moloney | Donna Moss |
| Richard Schiff | Toby Ziegler |
| John Spencer | Leo McGarry |
| Bradley Whitford | Josh Lyman |
| Martin Sheen | President Josiah Bartlet |
| Tim Matheson | Vice President John Hoynes |
| David Dunard | Alcoholic Politician |
| Randy Oglesby | Alcoholic Politician |
| Felton Perry | Alcoholic Politician |
| NiCole Robinson | Margaret Hooper |
| Jim Jansen | HUD Secretary Bill Fisher |
| Kim Webster | Ginger |
| Tim Van Pelt | Harry |
| William Duffy | Larry |
| Peter James Smith | Ed |
| Sean Allen Jones | Uniformed Secret Service Agent |