| Charlie Hunnam | Jackson 'Jax' Teller |
| Katey Sagal | Gemma Teller Morrow |
| Mark Boone Junior | Robert 'Bobby Elvis' Munson |
| Dayton Callie | Wayne Unser |
| Kim Coates | Alexander 'Tig' Trager |
| Tommy Flanagan | Filip 'Chibs' Telford |
| Theo Rossi | Juan Carlos 'Juice' Ortiz |
| Maggie Siff | Dr. Tara Knowles |
| Ron Perlman | Clarence 'Clay' Morrow |
| Jimmy Smits | Nero Padilla |
| Donal Logue | Lee Toric |
| Peter Weller | Charles 'Charlie' Barosky |
| Drea de Matteo | Wendy Case |
| Michael Ornstein | Chuck 'Chucky' Marstein |
| David Labrava | Happy Lowman |
| Winter Ave Zoli | Lyla Winston |
| Robin Weigert | Ally Lowen |
| Billy Brown | August Marks |
| Kim Dickens | Colette Jane |
| Niko Nicotera | George 'Ratboy' Skogstrom |
| Chris Reed | Philip 'Filthy Phil' Russell
(as Christopher Douglas Reed) |
| Kristen Renton | Ima Tite |
| Reynaldo Gallegos | Fiasco
(as Rey Gallegos) |
| Bridget Regan | Escort |
| Anthony Azizi | Amir Ghanezi |
| Samaire Armstrong | Darvany Jennings |
| Dave Navarro | Arcadio |
| Tate Berney | Young Boy |
| Hal Ozsan | Kia Ghanezi |
| Ryder Londo | Abel |
| Rusty Coones | Rane Quinn |
| Gylberto Eusebio | Lucius Padilla |
| Mario Perez | Gomes |
| Andre Brooks | Stockton Cop |
| Chasty Ballesteros | Cute Hooker |
| John Lewis | Dino |
| Natalie Skyy | Olsen Twin /
Bartender
(uncredited) |
| Angie Stevenson | Crow Eater
(uncredited) |
| Kurt Sutter | Otto 'Big Otto' Delaney
(uncredited) |